As reported by YARA:

YARA is multi-platform, running on Windows, Linux and Mac OS X, and can be used through its command-line interface or from your own Python scripts with the yara-python extension. If you plan to use YARA to scan compressed files (.zip, .tar, etc) you should take a look at yextend, a very helpful extension to YARA developed and open-sourced by Bayshore Networks.

Read the full story here:

Yara in a Nutshell